<%@ page language="java" import="java.util.*" pageEncoding="UTF-8"%>
<%
String path = request.getContextPath();
String basepath = request.getScheme()+"://"+request.getServerName()+":"+request.getServerPort()+path+"/";
%>

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN">
<html>
  <head>
    
    <title>SGA - SGA</title>
	<meta http-equiv="content-type" content="text/html; charset=utf-8">
	<script type="text/javascript">
		var _gaq = _gaq || [];
		_gaq.push(['_setaccount', 'ua-25011966-1']);
		_gaq.push(['_trackpageview']);
		(function() {
			var ga = document.createelement('script'); ga.type = 'text/javascript'; ga.async = true;
    		ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js';
    		var s = document.getelementsbytagname('script')[0]; s.parentnode.insertbefore(ga, s);
  		})();
  	</script>
  	<link rel="stylesheet" type="text/css" href="../inc/css/menu.css" />
<script type="text/javascript" language="javascript" src="../inc/js/menu.js"></script>
<script type="text/javascript" language="javascript" src="../inc/js/lib/jquery-1.6.1.min.js"></script>
 <script>
  $(document).ready(function () {
  	menuSlider.init('menu','slide')
  });
 </script>
  </head>
  
<body bgcolor="#ffffff">
<jsp:include page="./common/top.jsp">
			<jsp:param value="1" name="currentItem"/>
		</jsp:include>
<table style="border-collapse: collapse" height="420" cellspacing="0" cellpadding="0" width="900" border=0 align=center>
	<tbody>
	<tr><td height=25 colspan=2 valign="top"><hr color="#3333cc"></td></tr>
		  
	<tr>
	<td height=354 colspan=2 valign="top"><p class="words">
<b><font color=red>drygin</font> is a database of quantitative genetic interactions of <i>s. cerevisiae</i> derived from the sga double-mutant arrays conducted in <a href=http://www.utoronto.ca/boonelab/index.shtml target=_blank>boone lab</a> at <a href=http://tdccbr.med.utoronto.ca target=_blank>terrence donnelly centre for cellular and biochemical research</a>, <a href="http://www.utoronto.ca" target=_blank>university of toronto</a>. <br><br>current version of drygin is 1.0 (<a href="drygin_help.html" target=_blank>drygin documentation</a>).</b></font></p>
              
	<table>
	<tr height=50><td colspan=2 bgcolor=#ccccff><font class=words><font color = darkred><b>&nbsp;&nbsp;latest database statistics</b>
	<!--<ul><li>total sga genetic interactions in drygin: 5,486,458 -->
	<ul><li>total sga genetic interactions in drygin: 5,482,948
	<!--<li>total genes screened: 1,712 query (1,673 orfs) x 3,885 array (3,885 orfs)-->
	<li>total genes screened: 1,711 query (1,672 orfs) x 3,885 array (3,885 orfs)
	<li><b>updates:</b></br>
2010-02-10:&#9;the database was updated with the latest values from costanzo et al., 2010.</br>
2010-11-18:&#9;the <i>clc1&delta;</i> screen was removed because an allele discrepancy was noticed.</br>

	<!--<li>update (february 10th, 2010). the database was updated with the latest values from <a href=http://www.sciencemag.org/cgi/content/abstract/327/5964/425" target=_blank style="text-decoration: none">costanzo <i>et al.</i>, 2010</a></ul> -->
	</font></font></td></tr>
	<tr><td colspan=2 height=10><font class=words>for description of the database content, please refer to <a href="http://nar.oxfordjournals.org/cgi/content/abstract/gkp820" target=_blank style="text-decoration: none">judice l.y. koh, huiming ding, michael costanzo, anastasia baryshnikova, kiana toufighi, gary d. bader, chad l. myers, brenda j. andrews, and charles boone. drygin: a database of quantitative genetic interaction networks in yeast. <i>nucleic acids research</i>, 2010, vol. 38, database issue d502-d507.</a></font></td></tr>

	<tr height=50><td><img src="../images/searchgene.jpg" height=40></td><td><font class=words>&nbsp;<b><a onclick="return top.js.openextlink(window,event,this)" href="./visualization/interactions.html" target=_self>search genes</a></b> - query sga genetic interactions using gene names or orfs. download interactions or visualize network or clustergram, with genes color-coded according to functional annotations.</font></td></tr>
	<tr height=50><td><img src="../images/subnetwork.jpg" height=40></td><td><font class=words>&nbsp;<b><a onclick="return top.js.openextlink(window,event,this)" href="./clusters/clusters.html" target=_self>sub-networks</a></b> - search and visualize sub-networks of genetic interactions between a group of genes.</font></td></tr>
	<tr height=50><td><img src="../images/complex.jpg" height=40></td><td><font class=words>&nbsp;<b><a onclick="return top.js.openextlink(window,event,this)" href="./advanced/advsearch.html"	target=_self>search complexes/pathways</a></b> - search and visualize sga genetic interactions in known protein complexes and pathways.</font></td></tr>
	<tr height=50><td><img src="../images/integrated.jpg" height=40></td><td><font class=words>&nbsp;<b><a onclick="return top.js.openextlink(window,event,this)" href="./integrated/integrated.html" target=_self>overlap with biogrid</a></b> - search for sga genetic interactions that overlap with biogrid genetic and physical interactions.</font></td></tr>
	<tr height=50><td><img src="../images/download.jpg" height=40></td><td>&nbsp;<font class=words><b><a onclick="return top.js.openextlink(window,event,this)" href="./download/download.html" target=_self>download</a></b> - download latest sga genetic interactions in cytoscape sif, tab-delimited, or java treeview cdt formats.</font></td></tr>
	</table>
	<p align=center>
	</td>
	</tr>
	<jsp:include page="./common/bottom.jsp"></jsp:include>
	</tbody>
</table>
</body>